Tagged: Drug Development

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Medicinal Chemistry: Lead Modification and Optimization

Medicinal chemistry lays the foundation for the drug discovery process. A strong lead compound increases the chances of a pharmaceutical company developing a strong drug candidate, with better chances of success later on. Once a lead compound or ‘hit’ has...

96 well plates high throughput screening

Medicinal Chemistry: Lead Discovery and Identification

Medicinal chemistry lays the foundation for the drug discovery process. A strong lead compound increases the chances of a pharmaceutical company developing a strong drug candidate, with better chances of success later on. However, choosing a compound from a library...

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New Ebola Drugs Signal End for Deadly Virus

A major milestone in drug discovery and development was achieved in the summer of 2019. Two drug candidates developed to combat the Ebola epidemic in Africa – REGN-EB3 and mAb114 – produced remarkable results in clinical trials, effectively neutralizing the...

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Lipitor – The World’s All-Time Best Selling Drug

Since the 1950s, pharmaceutical companies have raced to discover and develop billion-dollar blockbuster drugs. In the face of stiff competition, only a handful are able to remain relevant over the course of many years; Rituxan, Advair and Humira are several...