Tagged: Drug Design

medicinal chemist holding drug candidates

Medicinal Chemistry: Lead Modification and Optimization

Medicinal chemistry lays the foundation for the drug discovery process. A strong lead compound increases the chances of a pharmaceutical company developing a strong drug candidate, with better chances of success later on. Once a lead compound or ‘hit’ has...

96 well plates high throughput screening

Medicinal Chemistry: Lead Discovery and Identification

Medicinal chemistry lays the foundation for the drug discovery process. A strong lead compound increases the chances of a pharmaceutical company developing a strong drug candidate, with better chances of success later on. However, choosing a compound from a library...

ebola treatment quarantine room biohazard

New Ebola Drugs Signal End for Deadly Virus

A major milestone in drug discovery and development was achieved in the summer of 2019. Two drug candidates developed to combat the Ebola epidemic in Africa – REGN-EB3 and mAb114 – produced remarkable results in clinical trials, effectively neutralizing the...

GPCR membrane bound receptor ligand

G-Protein-Coupled Receptors in Drug Discovery

G-protein-coupled receptors (GPCRs) play a big role in the human body. As they maintain many of our key functions, much research is done to better understand the structure and function of GPCRs. In addition, GPCRs are potential starting points in...