Category: Structure-Based Design

Cytochrome P450 Enzymes: Meet the Superfamily

Metabolism is described as the series of chemical reactions required to sustain life; when it comes to drug metabolism, no one does it better than the cytochrome P450 (CYP450) family of enzymes. Understanding of key enzymes within this superfamily –...

New Approaches to Peptide-Based Drugs

Pharmaceutical AbbVie’s Humira for the treatment of rheumatoid arthritis recorded sales of USD 16 billion in 2016 alone. As the pharmaceutical industry as a whole looks beyond small molecules to biologicals as therapeutics, there has been increasing interest and investment...