Category: Structure-Based Design

microbiology DNA molecules

Strategies to Combat Antibiotic Resistance

Drug resistance is a common issue in drug discovery programs. After the long and expensive process of developing a drug, the last thing you want is to find that it doesn’t provide a therapeutic effect. Drug resistance is prevalent in...

medicinal chemist holding drug candidates

Medicinal Chemistry: Lead Modification and Optimization

Medicinal chemistry lays the foundation for the drug discovery process. A strong lead compound increases the chances of a pharmaceutical company developing a strong drug candidate, with better chances of success later on. Once a lead compound or ‘hit’ has...