Category: Structure-Based Design

For those with a basic knowledge of chemistry, we delve into the techniques researchers use to develop the next big ‘blockbuster’ compound

96 well plates high throughput screening

Medicinal Chemistry: Lead Discovery and Identification

Medicinal chemistry lays the foundation for the drug discovery process. A strong lead compound increases the chances of a pharmaceutical company developing a strong drug candidate, with better chances of success later on. However, choosing a compound from a library...

green chemistry recycle logo molecules

Green Chemistry in Synthesis – The 12 Principles

In the 1990s, chemists began to better understand the impact of their activities on safety and sustainability, and took steps to address these issues. What followed was the adoption of certain practices that improved safety and reduced the environmental impact...

GPCR membrane bound receptor ligand

G-Protein-Coupled Receptors in Drug Discovery

G-protein-coupled receptors (GPCRs) play a big role in the human body. As they maintain many of our key functions, much research is done to better understand the structure and function of GPCRs. In addition, GPCRs are potential starting points in...